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Basic information of GAPDH :

Official Symbol of Gene GAPDH
Species Homo sapiens
Entrez Gene ID 2597
Official Full Name glyceraldehyde-3-phosphate dehydrogenase
Also known as G3PD; GAPD; HEL-S-162eP
Gene Type protein coding
dbXrefs Ensembl:ENSG00000111640 MIM:138400; AllianceGenome:HGNC:4141
Map Location 12p13.31

Sample information of multiple sclerosis:

Detected Sample blood
Sample Detail N/A
Detected Method qc-PCR
Disease MS
Disease subtype RRMS
Population N/A
Sample Size 92 IFNβ-treated MS patients / 99 MS patients never treated with IFNβ or other immunosuppressive therapy (treatment-nave patients) and 17 healthy volunteers

Literature information of multiple sclerosis :

Pubmed ID 12601105
Year 2003
Title Persistent neutralizing antibodies abolish the interferon beta bioavailability in MS patients

Results of multiple sclerosis :

Expression up-regulation
Risk type Treatment risk
Result IFNβ-treated patients showed a mean MxA mRNA expression , which was 11-fold higher than the level observed with treatment-nave patients and threefold higher than the upper threshold of normal.This result indicates a clear induction of MxA mRNA expression following IFNβ administration.
Mechanism/Pathway N/A