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Basic information of HLA-C :

Official Symbol of Gene HLA-C
Species Homo sapiens
Entrez Gene ID 3107
Official Full Name major histocompatibility complex, class I, C
Also known as MHC; HLAC; HLC-C; D6S204; PSORS1; HLA-JY3
Gene Type protein coding
dbXrefs Ensembl:ENSG00000204525 MIM:142840; AllianceGenome:HGNC:4933
Map Location 6p21.33

Sample information of multiple sclerosis:

Detected Sample PBMC
Sample Detail N/A
Detected Method RT-PCR
Disease MS
Disease subtype RRMS
Population N/A
Sample Size 24 treatment-nave RRMS patients / 39 healthy controls

Literature information of multiple sclerosis :

Pubmed ID 23401127
Year 2013
Title Altered expression of the plasminogen activation pathway in peripheral blood mononuclear cells in multiple sclerosis: possible pathomechanism of matrix metalloproteinase activation

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result HLA-C was found to have higher expression in the RRMS cases compared to the controls.
Mechanism/Pathway N/A