Basic information of HLA-DRB5 :
| Official Symbol of Gene | HLA-DRB5 |
| Species | Homo sapiens |
| Entrez Gene ID | 3127 |
| Official Full Name | major histocompatibility complex, class II, DR beta 5 |
| Also known as | DRB5; HLA-DRB5* |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000198502 MIM:604776; AllianceGenome:HGNC:4953 |
| Map Location | 6p21.32 |
Sample information of multiple sclerosis:
| Detected Sample | PBMC |
| Sample Detail | N/A |
| Detected Method | RT-PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | N/A |
| Sample Size | 13 interferon-β treated RRMS patients / 39 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 23401127 |
| Year | 2013 |
| Title | Altered expression of the plasminogen activation pathway in peripheral blood mononuclear cells in multiple sclerosis: possible pathomechanism of matrix metalloproteinase activation |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | This gene was also over-expressed in RRMS patients receiving INF-β therapy. |
| Mechanism/Pathway | N/A |
