Basic information of IL1B :
| Official Symbol of Gene | IL1B |
| Species | Homo sapiens |
| Entrez Gene ID | 3553 |
| Official Full Name | interleukin 1 beta |
| Also known as | IL-1; IL1F2; IL1beta; IL1-BETA |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000125538 MIM:147720; AllianceGenome:HGNC:5992 |
| Map Location | 2q14.1 |
Sample information of multiple sclerosis:
| Detected Sample | PBMC |
| Sample Detail | N/A |
| Detected Method | qRT-PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | N/A |
| Sample Size | 18 RRMS patients / 21 HCs |
Literature information of multiple sclerosis :
| Pubmed ID | 25458313 |
| Year | 2015 |
| Title | Increased inflammasome related gene expression profile in PBMC may facilitate T helper 17 cell induction in multiple sclerosis |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | mRNA levels of IL-1β were significantly higher in RRMS patients compared to HC. |
| Mechanism/Pathway | Pathogenic Th17 cells can be induced by a cytokine cocktail containing IL-1β, which is a potent pro-inflammatory cytokine. |
