Details

Home Details


Basic information of FCRL2 :

Official Symbol of Gene FCRL2
Species Homo sapiens
Entrez Gene ID 79368
Official Full Name Fc receptor like 2
Also known as FCRH2; IFGP4; IRTA4; SPAP1; CD307b; SPAP1A; SPAP1B; SPAP1C
Gene Type protein coding
dbXrefs Ensembl:ENSG00000132704 MIM:606509; AllianceGenome:HGNC:14875
Map Location 1q23.1

Sample information of multiple sclerosis:

Detected Sample PBMC
Sample Detail N/A
Detected Method RT-PCR
Disease MS
Disease subtype RRMS
Population N/A
Sample Size 22 patients with low neurodegeneration phenotypes / 23 patients with high neurodegeneration phenotypes

Literature information of multiple sclerosis :

Pubmed ID 26604134
Year 2015
Title MRI phenotypes with high neurodegeneration are associated with peripheral blood B-cell changes

Results of multiple sclerosis :

Expression down-regulation
Risk type Disease risk
Result Level for this gene was significantly down-regulated in PBMC from patients with MRI phenotypes characterized by high neurodegeneration
Mechanism/Pathway N/A