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Basic information of CD22 :

Official Symbol of Gene CD22
Species Homo sapiens
Entrez Gene ID 933
Official Full Name CD22 molecule
Also known as SIGLEC2; SIGLEC-2
Gene Type protein coding
dbXrefs Ensembl:ENSG00000012124 MIM:107266; AllianceGenome:HGNC:1643
Map Location 19q13.12

Sample information of multiple sclerosis:

Detected Sample PBMC
Sample Detail N/A
Detected Method RT-PCR
Disease MS
Disease subtype RRMS
Population N/A
Sample Size 22 patients with low neurodegeneration phenotypes / 23 patients with high neurodegeneration phenotypes

Literature information of multiple sclerosis :

Pubmed ID 26604134
Year 2015
Title MRI phenotypes with high neurodegeneration are associated with peripheral blood B-cell changes

Results of multiple sclerosis :

Expression down-regulation
Risk type Disease risk
Result Level for this gene was significantly down-regulated in PBMC from patients with MRI phenotypes characterized by high neurodegeneration
Mechanism/Pathway N/A