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Basic information of APOE :

Official Symbol of Gene APOE
Species Homo sapiens
Entrez Gene ID 348
Official Full Name apolipoprotein E
Also known as AD2; LPG; APO-E; ApoE4; LDLCQ5
Gene Type protein coding
dbXrefs Ensembl:ENSG00000130203 MIM:107741; AllianceGenome:HGNC:613
Map Location 19q13.32

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail N/A
Detected Method N/A
Disease MS
Disease subtype N/A
Population N/A
Sample Size 205 MS patients

Literature information of multiple sclerosis :

Pubmed ID 11311368
Year 2001
Title AD gene accelerates MS

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result They found that MS patients who also carried the APOE4 gene, had MS an average of three years earlier and suffered a quicker and more serious decline in health.
Mechanism/Pathway APOE genes, which are involved in the transport of fats, might help repair or damage myelin.