Basic information of VDR :

Official Symbol of Gene	VDR
Species	Homo sapiens
Entrez Gene ID	7421
Official Full Name	vitamin D receptor
Also known as	NR1I1; PPP1R163
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000111424 MIM:601769; AllianceGenome:HGNC:12679
Map Location	12q13.11

Sample information of multiple sclerosis:

Detected Sample	peripheral blood
Sample Detail	N/A
Detected Method	qPCR
Disease	MS
Disease subtype	RRMS,SPMS
Population	N/A
Sample Size	72 MS patients(35 sporadic,37 familial MS patients)/74 controls(34 healthy first-degree relatives of the familial MS patients (HFR),40 healthy individuals )

Literature information of multiple sclerosis :

Pubmed ID	33833274
Year	2021
Title	Gene expression profiles of YAP1, TAZ, CRB3, and VDR in familial and sporadic multiple sclerosis among an Iranian population

Results of multiple sclerosis :

Expression	up-regulation
Risk type	Disease risk
Result	The results showed the increased expression of VDR in the sporadic group, as compared to other groups.
Mechanism/Pathway	The Hippo pathway is an important mediator of myelination in the nervous system and might contribute to the pathophysiology of MS.VDR is the key effector of the Hippo pathway.