Basic information of DDT :
| Official Symbol of Gene | DDT |
| Species | Homo sapiens |
| Entrez Gene ID | 1652 |
| Official Full Name | D-dopachrome tautomerase |
| Also known as | D-DT; DDCT; MIF2; MIF-2 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000099977 MIM:602750; AllianceGenome:HGNC:2732 |
| Map Location | 22q11.23 |
Sample information of multiple sclerosis:
| Detected Sample | plasma |
| Sample Detail | N/A |
| Detected Method | Real-Time PCR |
| Disease | MS |
| Disease subtype | CIS-MS,RRMS,PPMS,SPMS |
| Population | Male |
| Sample Size | 123 MS / 35 HCs |
Literature information of multiple sclerosis :
| Pubmed ID | 28923927 |
| Year | 2017 |
| Title | MIF and D-DT are potential disease severity modifiers in male MS subjects |
Results of multiple sclerosis :
| Expression | No significance |
| Risk type | Disease risk |
| Result | D-DT levels were also somewhat elevated in MS subjects compared with HC, but this difference did not reach significance. |
| Mechanism/Pathway | D-DT has a neuroinflammatory role and similarly affects cell migration. |
