Basic information of MALAT1 :
| Official Symbol of Gene | MALAT1 |
| Species | Homo sapiens |
| Entrez Gene ID | 378938 |
| Official Full Name | metastasis associated lung adenocarcinoma transcript 1 |
| Also known as | HCN; NEAT2; PRO2853; LINC00047; NCRNA00047 |
| Gene Type | ncRNA |
| dbXrefs | Ensembl:ENSG00000251562 MIM:607924; AllianceGenome:HGNC:29665 |
| Map Location | 11q13.1 |
Sample information of multiple sclerosis:
| Detected Sample | serum |
| Sample Detail | N/A |
| Detected Method | qRT-PCR |
| Disease | MS |
| Disease subtype | RRMS,SPMS |
| Population | Egyptian |
| Sample Size | 45 MS patients / 45 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 30514825 |
| Year | 2019 |
| Title | LncRNAs, MALAT1 and lnc-DC as potential biomarkers for multiple sclerosis diagnosis |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | MALAT1 was significantly increased in MS patients in comparison with controls. |
| Mechanism/Pathway | In respect to its role in nervous system, MALAT1 has regulated gene expression in neurons that involved in nuclear and synapse function and synaptogenesis. |
