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Basic information of TCHH :

Official Symbol of Gene TCHH
Species Homo sapiens
Entrez Gene ID 7062
Official Full Name trichohyalin
Also known as THH; THL; TRHY; UHS3
Gene Type protein coding
dbXrefs Ensembl:ENSG00000159450 MIM:190370; AllianceGenome:HGNC:11791
Map Location 1q21.3

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail N/A
Detected Method N/A
Disease N/A
Disease subtype N/A
Population N/A
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 8533414
Year 1995
Title Multiple sclerosis.

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result They show an overactivity of a subset of CD4+ T-helper cells known as Thl cells.
Mechanism/Pathway These activated T cells, present systemically in patients with multiple sclerosis, secrete interferon gamma (IFN--y). Their activation is dependent on cytokine interleukin (IL)-12 secreted by macrophages and inhibited by cytokines IL- 10 and IL-4.