Basic information of GAPVD1 :
| Official Symbol of Gene | GAPVD1 |
| Species | Homo sapiens |
| Entrez Gene ID | 26130 |
| Official Full Name | GTPase activating protein and VPS9 domains 1 |
| Also known as | RAP6; GAPEX5; GAPex-5 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000165219 MIM:611714; AllianceGenome:HGNC:23375 |
| Map Location | 9q33.3 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | PBMC |
| Detected Method | RT-PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | Iranian |
| Sample Size | RRMS patients (n = 200) and a healthy control group (n = 200) |
Literature information of multiple sclerosis :
| Pubmed ID | 33548618 |
| Year | 2021 |
| Title | An interdependence between GAPVD1 gene polymorphism, expression level and response to interferon beta in patients with multiple sclerosis |
Results of multiple sclerosis :
| Expression | down-regulation |
| Risk type | Disease risk |
| Result | The results show that the GAPVD1 expression level and rs2291858 genotype probably affect the response to IFN-β in patients with MS. |
| Mechanism/Pathway | affect the response to IFN- β in patients with MS. |
