Details

Home Details


Basic information of MIR326 :

Official Symbol of Gene MIR326
Species Homo sapiens
Entrez Gene ID 442900
Official Full Name microRNA 326
Also known as MIRN326; mir-326; hsa-mir-326
Gene Type ncRNA
dbXrefs Ensembl:ENSG00000199090 MIM:613755; miRBase:MI0000808; AllianceGenome:HGNC:31769
Map Location 11q13.4

Sample information of multiple sclerosis:

Detected Sample blood samples
Sample Detail PBLs
Detected Method RT-PCR
Disease MS
Disease subtype RRMS
Population Isfahan
Sample Size 40RRMS 20healthy controls

Literature information of multiple sclerosis :

Pubmed ID 24792898
Year 2014
Title miR-326 and miR-26a, twopotential markers for diagnosis ofrelapse and remission phases in patient with relapsing–remitting multiple sclerosis

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result Our results confirmed potential ofmiR-326 as a diagnostic biomarker to discriminate between relapsing and remitting phases ofmultiple sclerosis disease
Mechanism/Pathway We observed up-regulation of both miR-326 and miR-26a in relapsing phase ofmultiple sclerosis patients compared with remitting phase (p value = 0.0001) and healthy controls (p value = 0.0091)