Basic information of STAT4 :

Official Symbol of Gene	STAT4
Species	Homo sapiens
Entrez Gene ID	6775
Official Full Name	signal transducer and activator of transcription 4
Also known as	SLEB11
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000138378 MIM:600558; AllianceGenome:HGNC:11365
Map Location	2q32.2-q32.3

Sample information of multiple sclerosis:

Detected Sample	peripheral blood
Sample Detail	N/A
Detected Method	RT-PCR
Disease	MS
Disease subtype	N/A
Population	Spanish
Sample Size	575 with RA, 440 with multiple sclerosis, 700 with inflammatory bowel disease, 311 with type 1 diabetes, and 723 ethnically matched healthy control subjects

Literature information of multiple sclerosis :

Pubmed ID	18759272
Year	2008
Title	Association of the STAT4 Gene With Increased Susceptibility for Some Immune-Mediated Diseases

Results of multiple sclerosis :

Expression	up-regulation
Risk type	Disease risk
Result	The STAT4 gene is emerging as a novel common risk factor for diverse complex diseases.
Mechanism/Pathway	The STAT4 gene encodes a transcription factor involved in the signaling pathways of several cytokines, including interleukin-12 (IL-12), the type I interferons, and IL-23.