Basic information of SEMA3A :
| Official Symbol of Gene | SEMA3A |
| Species | Homo sapiens |
| Entrez Gene ID | 10371 |
| Official Full Name | semaphorin 3A |
| Also known as | HH16; SemD; COLL1; SEMA1; SEMAD; SEMAL; coll-1; Hsema-I; SEMAIII; Hsema-III |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000075213 MIM:603961; AllianceGenome:HGNC:10723 |
| Map Location | 7q21.11 |
Sample information of multiple sclerosis:
| Detected Sample | whole blood |
| Sample Detail | N/A |
| Detected Method | qRT-PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | Iranic |
| Sample Size | Twenty healthy controls and 105 RRMS patients, |
Literature information of multiple sclerosis :
| Pubmed ID | 32497464 |
| Year | 2020 |
| Title | Gene expression of semaphorin-3A, semaphorin-7A, neuropilin-1, plexin-C1, and å°¾1 integrin in treated-multiple sclerosis patients |
Results of multiple sclerosis :
| Expression | down-regulation |
| Risk type | Disease risk |
| Result | Our findings confirm that the presence of Sema3A, Sema7A, and their receptors can play critical roles in the treatment of MS patients. Therefore, they can be potential target molecules for MS treatment in the future. |
| Mechanism/Pathway | immunomodulatory effect |
