Basic information of ITGB1 :
| Official Symbol of Gene | ITGB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3688 |
| Official Full Name | integrin subunit beta 1 |
| Also known as | CD29; FNRB; MDF2; VLAB; GPIIA; MSK12; VLA-BETA |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000150093 MIM:135630; AllianceGenome:HGNC:6153 |
| Map Location | 10p11.22 |
Sample information of multiple sclerosis:
| Detected Sample | whole blood |
| Sample Detail | N/A |
| Detected Method | qRT-PCR,Microarray |
| Disease | MS |
| Disease subtype | RRMS |
| Population | Iranic |
| Sample Size | Twenty healthy controls and 105 RRMS patients, |
Literature information of multiple sclerosis :
| Pubmed ID | 32497464 |
| Year | 2020 |
| Title | Gene expression of semaphorin-3A, semaphorin-7A, neuropilin-1, plexin-C1, and å°¾1 integrin in treated-multiple sclerosis patients |
Results of multiple sclerosis :
| Expression | N/A |
| Risk type | Disease risk |
| Result | expression of NP-1 (P < 0.001), plexin-C1 (P < 0.001), and å°¾1 integrin (P < 0.05) only increased in patients receiving high-dose IFN-å°¾1a, IFN-å°¾1b, and GA |
| Mechanism/Pathway | immunomodulatory effect |
