Basic information of KL :
| Official Symbol of Gene | KL |
| Species | Homo sapiens |
| Entrez Gene ID | 9365 |
| Official Full Name | klotho |
| Also known as | KLA; HFTC3 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000133116 MIM:604824; AllianceGenome:HGNC:6344 |
| Map Location | 13q13.1 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | PBMCs |
| Detected Method | RT-PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | Iranic |
| Sample Size | 30 patients with relapsing-remitting MS (RRMS) along with 30 age and sexmatched healthy individuals |
Literature information of multiple sclerosis :
| Pubmed ID | 28991703 |
| Year | 2017 |
| Title | Klotho gene expression decreases in peripheral blood mononuclear cells (PBMCs) of patients with relapsing-remitting multiple sclerosis |
Results of multiple sclerosis :
| Expression | down-regulation |
| Risk type | Disease risk |
| Result | The results showed that klotho gene expression in the PBMCs of patients with RRMS is nearly 2.5-fold less than healthy individuals |
| Mechanism/Pathway | anti-aging and anti-inflammatory |
