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Basic information of HOTAIR :

Official Symbol of Gene HOTAIR
Species Homo sapiens
Entrez Gene ID 100124700
Official Full Name HOX transcript antisense RNA
Also known as HOXAS; HOXC-AS4; HOXC11-AS1; NCRNA00072
Gene Type ncRNA
dbXrefs Ensembl:ENSG00000228630 MIM:611400; AllianceGenome:HGNC:33510
Map Location 12q13.13

Sample information of multiple sclerosis:

Detected Sample whole blood
Sample Detail PBMCs
Detected Method RT-PCR
Disease MS
Disease subtype N/A
Population Iranian
Sample Size Forty-two patients with relapsing–remitting MS,32 age- and gender-matched healthy controls

Literature information of multiple sclerosis :

Pubmed ID 29030863
Year 2017
Title HOTAIR but not ANRIL long non-coding RNA contributes to the pathogenesis of multiple sclerosis

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result expression of HOTAIR and ANRIL is probably not affected by VD and/or inflammation in THP-1 cells in vitro
Mechanism/Pathway potent inflammatory milieu