Basic information of BDKRB1 :

Official Symbol of Gene	BDKRB1
Species	Homo sapiens
Entrez Gene ID	623
Official Full Name	bradykinin receptor B1
Also known as	B1R; BKR1; B1BKR; BKB1R; BRADYB1
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000100739 MIM:600337; AllianceGenome:HGNC:1029
Map Location	14q32.2

Sample information of multiple sclerosis:

Detected Sample	whole blood
Sample Detail	PBMCs
Detected Method	RT-PCR
Disease	MS
Disease subtype	N/A
Population	N/A
Sample Size	6 patients with multiple sclerosis and 8 healthy control

Literature information of multiple sclerosis :

Pubmed ID	15883268
Year	2005
Title	Kinin B1 Receptor Expression on Multiple Sclerosis Mononuclear Cells

Results of multiple sclerosis :

Expression	down-regulation
Risk type	Disease risk
Result	The time-course kinin B1 –actin mRNA ratio correlated positively with the Expanded Disability Status Scale index (P.001), occurrence ofclinical relapse (P=.02), volume oflesion on T2-weighted images (P.003) and interleukin 2 receptor and major histocompatibility complex class II expressiononCD4lymphocytes,butnotwithgadolinium-enhancing lesions. The time-course kinin B1 – actin mRNA ratios were 5 to 25 times lower in samples derived from healthy controls.
Mechanism/Pathway	N/A