Basic information of miR-155 :
| Official Symbol of Gene | miR-155 |
| Species | Homo sapiens |
| Entrez Gene ID | 406947 |
| Official Full Name | microRNA 155 |
| Also known as | MIRN155; mir-155; miRNA155 |
| Gene Type | ncRNA |
| dbXrefs | Ensembl:ENSG00000283904 MIM:609337; miRBase:MI0000681; AllianceGenome:HGNC:31542 |
| Map Location | 21q21.3 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | peripheral blood mononuclear cells |
| Detected Method | N/A |
| Disease | MS |
| Disease subtype | RRMS |
| Population | N/A |
| Sample Size | 25 RRMS patients and 10 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 34171684 |
| Year | 2021 |
| Title | miR-155 and functional proteins of CD8+ T cells as potential prognostic biomarkers for relapsing-remitting multiple sclerosis |
Results of multiple sclerosis :
| Expression | up-regulated |
| Risk type | Disease risk |
| Result | Results showed downregulation of miR-155 and upregulation of surface receptors and cytotoxic proteins in CD8+T cells with significant correlation with each other and patients’ EDSS. |
| Mechanism/Pathway | miR-155 was found to be a providential biomarker as it was found upregulated in peripheral blood mononuclear cells (PBMCs). |
