Basic information of ICAM1 :
| Official Symbol of Gene | ICAM1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3383 |
| Official Full Name | intercellular adhesion molecule 1 |
| Also known as | BB2; CD54; P3.58 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000090339 MIM:147840; AllianceGenome:HGNC:5344 |
| Map Location | 19p13.2 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | French |
| Sample Size | 439 case–parent MS families |
Literature information of multiple sclerosis :
| Pubmed ID | 14551606 |
| Year | 2003 |
| Title | Intercellular adhesion molecule-1: a protective haplotype against multiple sclerosis |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | the genes encoding ICAM-1 receptors do not influence MS susceptibility or severity. ICAM-1 had a modest, but significant effect on MS genetic susceptibility, independent of HLA and disease severity. |
| Mechanism/Pathway | in the transmigration of inflammatory cells through the blood–brain barrier |
