Basic information of ATG5 :
| Official Symbol of Gene | ATG5 |
| Species | Homo sapiens |
| Entrez Gene ID | 9474 |
| Official Full Name | autophagy related 5 |
| Also known as | ASP; APG5; APG5L; hAPG5; SCAR25; APG5-LIKE |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000057663 MIM:604261; AllianceGenome:HGNC:589 |
| Map Location | 6q21 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood;brain |
| Sample Detail | T cell;Postmortem tissues |
| Detected Method | Real-time PCR |
| Disease | MS |
| Disease subtype | active relapsing-remitting MS |
| Population | N/A |
| Sample Size | N/A;10 |
Literature information of multiple sclerosis :
| Pubmed ID | 19066443 |
| Year | 2009 |
| Title | Elevated ATG5 expression in autoimmune demyelination and multiple sclerosis |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | Atg5 expression was significantly elevated in individuals with active relapsing-remitting MS compared to non-diseased controls |
| Mechanism/Pathway | modulate T cell survival |
