Basic information of HLA-DRA :

Official Symbol of Gene	HLA-DRA
Species	Homo sapiens
Entrez Gene ID	4947
Official Full Name	major histocompatibility complex, class II, DR alpha
Also known as	HLA-DRA1
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000204287 MIM:142860; AllianceGenome:HGNC:4947
Map Location	6p21.32

Sample information of multiple sclerosis:

Detected Sample	peripheral blood
Sample Detail	N/A
Detected Method	RT-PCR
Disease	MS
Disease subtype	N/A
Population	N/A
Sample Size	8 MS cases and 8 controls

Literature information of multiple sclerosis :

Pubmed ID	11086101
Year	2000
Title	Transcriptional analysis of multiple sclerosis brain lesions reveals a complex pattern of cytokine expression

Results of multiple sclerosis :

Expression	up-regulation
Risk type	Disease risk
Result	CD4 and HLA-DRalpha transcripts were dramatically increased in MS as compared with controls
Mechanism/Pathway	This reveals a robust MHC class II up-regulation and suggests that Ag is being presented locally to activated T cells