Basic information of CCR1 :
| Official Symbol of Gene | CCR1 |
| Species | Homo sapiens |
| Entrez Gene ID | 1602 |
| Official Full Name | C-C motif chemokine receptor 1 |
| Also known as | CKR1; CD191; CKR-1; HM145; CMKBR1; MIP1aR; SCYAR1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000163823 MIM:601159; AllianceGenome:HGNC:1602 |
| Map Location | 3p21.31 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | RT-PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | 8 MS cases and 8 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 11086101 |
| Year | 2000 |
| Title | Transcriptional analysis of multiple sclerosis brain lesions reveals a complex pattern of cytokine expression |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | Although analysis of cytokine and cytokine receptor genes expression showed predominantly increased levels of several Th1 molecules (TGF-ss, RANTES, and macrophage-inflammatory protein (MIP)-1alpha) in MS samples |
| Mechanism/Pathway | our data suggest a complex regulation of the inflammatory response in human autoimmune demyelination |
