Basic information of CCR5 :

Official Symbol of Gene	CCR5
Species	Homo sapiens
Entrez Gene ID	1608
Official Full Name	C-C motif chemokine receptor 5
Also known as	CKR5; CCR-5; CD195; CKR-5; CCCKR5; CMKBR5; IDDM22; CC-CKR-5
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000160791 MIM:601373; AllianceGenome:HGNC:1606
Map Location	3p21.31

Sample information of multiple sclerosis:

Detected Sample	peripheral blood
Sample Detail	N/A
Detected Method	RT-PCR
Disease	MS
Disease subtype	N/A
Population	N/A
Sample Size	8 MS cases and 8 controls

Literature information of multiple sclerosis :

Pubmed ID	11086101
Year	2000
Title	Transcriptional analysis of multiple sclerosis brain lesions reveals a complex pattern of cytokine expression

Results of multiple sclerosis :

Expression	up-regulation
Risk type	Disease risk
Result	Similarly, both proinflammatory type (CCR1, CCR5) and immunomodulatory type (CCR4, CCR8) chemokine receptors were differentially expressed in the MS brain
Mechanism/Pathway	our data suggest a complex regulation of the inflammatory response in human autoimmune demyelination