Basic information of CCR4 :

Official Symbol of Gene	CCR4
Species	Homo sapiens
Entrez Gene ID	1605
Official Full Name	C-C motif chemokine receptor 4
Also known as	CKR4; K5-5; CD194; CMKBR4; ChemR13; CC-CKR-4; HGCN:14099
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000183813 MIM:604836; AllianceGenome:HGNC:1605
Map Location	3p22.3

Sample information of multiple sclerosis:

Detected Sample	peripheral blood
Sample Detail	N/A
Detected Method	RT-PCR
Disease	MS
Disease subtype	N/A
Population	N/A
Sample Size	8 MS cases and 8 controls

Literature information of multiple sclerosis :

Pubmed ID	11086101
Year	2000
Title	Transcriptional analysis of multiple sclerosis brain lesions reveals a complex pattern of cytokine expression

Results of multiple sclerosis :

Expression	up-regulation
Risk type	Disease risk
Result	Similarly, both proinflammatory type (CCR1, CCR5) and immunomodulatory type (CCR4, CCR8) chemokine receptors were differentially expressed in the MS brain
Mechanism/Pathway	our data suggest a complex regulation of the inflammatory response in human autoimmune demyelination