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Basic information of CCR8 :

Official Symbol of Gene CCR8
Species Homo sapiens
Entrez Gene ID 1609
Official Full Name C-C motif chemokine receptor 8
Also known as CY6; TER1; CCR-8; CKRL1; CDw198; CMKBR8; GPRCY6; CMKBRL2; CC-CKR-8
Gene Type protein coding
dbXrefs Ensembl:ENSG00000179934 MIM:601834; AllianceGenome:HGNC:1609
Map Location 3p22.1

Sample information of multiple sclerosis:

Detected Sample peripheral blood
Sample Detail N/A
Detected Method RT-PCR
Disease MS
Disease subtype N/A
Population N/A
Sample Size 8 MS cases and 8 controls

Literature information of multiple sclerosis :

Pubmed ID 11086101
Year 2000
Title Transcriptional analysis of multiple sclerosis brain lesions reveals a complex pattern of cytokine expression

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result Similarly, both proinflammatory type (CCR1, CCR5) and immunomodulatory type (CCR4, CCR8) chemokine receptors were differentially expressed in the MS brain
Mechanism/Pathway our data suggest a complex regulation of the inflammatory response in human autoimmune demyelination