Basic information of STAT1 :
| Official Symbol of Gene | STAT1 |
| Species | Homo sapiens |
| Entrez Gene ID | 11362 |
| Official Full Name | signal transducer and activator of transcription 1 |
| Also known as | CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000115415 MIM:600555; AllianceGenome:HGNC:11362 |
| Map Location | 2q32.2 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | TaqMan RT-qPCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | 50 MS cases and 50 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 30412483 |
| Year | 2019 |
| Title | Analysis of STAT1, STAT2 and STAT3 mRNA expression levels in the blood of patients with multiple sclerosis |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | The results showed that STAT1 gene expression was significantly up-regulated |
| Mechanism/Pathway | The signal transducer and activator of transcription (STAT) family has an essential role in transmitting many of the cytokine-mediated signals and failure in the signaling process contributes to the etiopathogenesis of MS |
