Basic information of STAT2 :
| Official Symbol of Gene | STAT2 |
| Species | Homo sapiens |
| Entrez Gene ID | 11363 |
| Official Full Name | signal transducer and activator of transcription 2 |
| Also known as | P113; IMD44; ISGF-3; PTORCH3; STAT113 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000170581 MIM:600556; AllianceGenome:HGNC:11363 |
| Map Location | 12q13.3 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | TaqMan RT-qPCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | 50 MS cases and 50 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 30412483 |
| Year | 2019 |
| Title | Analysis of STAT1, STAT2 and STAT3 mRNA expression levels in the blood of patients with multiple sclerosis |
Results of multiple sclerosis :
| Expression | down-regulation |
| Risk type | Disease risk |
| Result | whereas STAT2 gene expression was significantly down-regulated (p< 0.0001) in MS patients compared to controls |
| Mechanism/Pathway | The signal transducer and activator of transcription (STAT) family has an essential role in transmitting many of the cytokine-mediated signals and failure in the signaling process contributes to the etiopathogenesis of MS |
