Details

Home Details


Basic information of STAT3 :

Official Symbol of Gene STAT3
Species Homo sapiens
Entrez Gene ID 11364
Official Full Name signal transducer and activator of transcription 3
Also known as APRF; HIES; ADMIO; ADMIO1
Gene Type protein coding
dbXrefs Ensembl:ENSG00000168610 MIM:102582; AllianceGenome:HGNC:11364
Map Location 17q21.2

Sample information of multiple sclerosis:

Detected Sample peripheral blood
Sample Detail N/A
Detected Method TaqMan RT-qPCR
Disease MS
Disease subtype N/A
Population N/A
Sample Size 50 MS cases and 50 controls

Literature information of multiple sclerosis :

Pubmed ID 30412483
Year 2019
Title Analysis of STAT1, STAT2 and STAT3 mRNA expression levels in the blood of patients with multiple sclerosis

Results of multiple sclerosis :

Expression N/A
Risk type Disease risk
Result there was no significant difference between MS patients and controls for STAT3 gene expression
Mechanism/Pathway The signal transducer and activator of transcription (STAT) family has an essential role in transmitting many of the cytokine-mediated signals and failure in the signaling process contributes to the etiopathogenesis of MS