Basic information of CLDN11 :

Official Symbol of Gene	CLDN11
Species	Homo sapiens
Entrez Gene ID	8514
Official Full Name	claudin 11
Also known as	OSP; OTM; HLD22
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000013297 MIM:601326; AllianceGenome:HGNC:8514
Map Location	3q26.2

Sample information of multiple sclerosis:

Detected Sample	peripheral blood
Sample Detail	N/A
Detected Method	qPCR
Disease	MS
Disease subtype	N/A
Population	N/A
Sample Size	13 men MS cases and 15 men controls

Literature information of multiple sclerosis :

Pubmed ID	26768647
Year	2016
Title	Leukocyte Gene Expression and Plasma Concentration in Multiple Sclerosis: Alteration of Transforming Growth Factor-βs, Claudin-11, and Matrix Metalloproteinase-2

Results of multiple sclerosis :

Expression	up-regulation
Risk type	Disease risk
Result	The results of this study showed that the gene expression of Claudin-11 was significantly higher in MS group compared with normal
Mechanism/Pathway	Leukocytes penetration into the blood-brain barrier is related to several factors, such as, the conversion of leukocyte gene expression or plasma characteristics