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Basic information of MMP2 :

Official Symbol of Gene MMP2
Species Homo sapiens
Entrez Gene ID 7166
Official Full Name matrix metallopeptidase 2
Also known as CLG4; MONA; CLG4A; MMP-2; TBE-1; MMP-II
Gene Type protein coding
dbXrefs Ensembl:ENSG00000087245 MIM:120360; AllianceGenome:HGNC:7166
Map Location 16q12.2

Sample information of multiple sclerosis:

Detected Sample peripheral blood
Sample Detail N/A
Detected Method qPCR
Disease MS
Disease subtype N/A
Population N/A
Sample Size 13 men MS cases and 15 men controls

Literature information of multiple sclerosis :

Pubmed ID 26768647
Year 2016
Title Leukocyte Gene Expression and Plasma Concentration in Multiple Sclerosis: Alteration of Transforming Growth Factor-βs, Claudin-11, and Matrix Metalloproteinase-2

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result the MMP-2 pattern was similar to Claudin-11 and correlated positively with it
Mechanism/Pathway Leukocytes penetration into the blood-brain barrier is related to several factors, such as, the conversion of leukocyte gene expression or plasma characteristics