Basic information of TGFB1 :
| Official Symbol of Gene | TGFB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 11766 |
| Official Full Name | transforming growth factor beta 1 |
| Also known as | CED; LAP; DPD1; TGFB; IBDIMDE; TGFbeta; TGF-beta1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000105329 MIM:190180; AllianceGenome:HGNC:11766 |
| Map Location | 19q13.2 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | qPCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | 13 men MS cases and 15 men controls |
Literature information of multiple sclerosis :
| Pubmed ID | 26768647 |
| Year | 2016 |
| Title | Leukocyte Gene Expression and Plasma Concentration in Multiple Sclerosis: Alteration of Transforming Growth Factor-βs, Claudin-11, and Matrix Metalloproteinase-2 |
Results of multiple sclerosis :
| Expression | down-regulation |
| Risk type | Disease risk |
| Result | although the expressions of TGF-β1 and TGF-β2 are down-regulated in the leukocytes of subjects with MS, they showed higher levels of these cytokines in blood plasma |
| Mechanism/Pathway | Leukocytes penetration into the blood-brain barrier is related to several factors, such as, the conversion of leukocyte gene expression or plasma characteristics |
