Basic information of APOA1 :

Official Symbol of Gene	APOA1
Species	Homo sapiens
Entrez Gene ID	600
Official Full Name	apolipoprotein A1
Also known as	HPALP2; apo(a)
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000118137 MIM:107680; AllianceGenome:HGNC:600
Map Location	11q23.3

Sample information of multiple sclerosis:

Detected Sample	peripheral blood
Sample Detail	N/A
Detected Method	RT-qPCR
Disease	MS
Disease subtype	N/A
Population	N/A
Sample Size	45 MS cases and 45 controls

Literature information of multiple sclerosis :

Pubmed ID	33086557
Year	2020
Title	Increased Pro-Thrombotic Platelet Activity Associated with Thrombin/PAR1-Dependent Pathway Disorder in Patients with Secondary Progressive Multiple Sclerosis

Results of multiple sclerosis :

Expression	down-regulation
Risk type	Disease risk
Result	The mRNA expression of gene coding α2M was upregulated, whilst ApoA1 was down-regulated, both in platelets and megakaryocytes from MS patients
Mechanism/Pathway	the high risk of ischemic events in multiple sclerosis (MS) that are associated with increased pro-thrombotic activity of blood platelets