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Basic information of TRADD :

Official Symbol of Gene TRADD
Species Homo sapiens
Entrez Gene ID 12030
Official Full Name TNFRSF1A associated via death domain
Also known as Hs.89862
Gene Type protein coding
dbXrefs Ensembl:ENSG00000102871 MIM:603500; AllianceGenome:HGNC:12030
Map Location 16q22.1

Sample information of multiple sclerosis:

Detected Sample peripheral blood
Sample Detail N/A
Detected Method RT-PCR
Disease MS
Disease subtype RRMS、SPMS、PPMS
Population N/A
Sample Size 23 relapsing remitting (RR), 19 secondary progressive (SP) and 12 primary progressive (PP) MS patients, as well as of 29 healthy controls

Literature information of multiple sclerosis :

Pubmed ID 24603611
Year 2014
Title FADD is upregulated in relapsing remitting multiple sclerosis

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result The median of TRADD expression was elevated in the patient groups compared to the healthy group, but this was not significant
Mechanism/Pathway an elevated general inflammatory activity