Basic information of FADD :
| Official Symbol of Gene | FADD |
| Species | Homo sapiens |
| Entrez Gene ID | 3573 |
| Official Full Name | Fas associated via death domain |
| Also known as | GIG3; IMD90; MORT1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000168040 MIM:602457; AllianceGenome:HGNC:3573 |
| Map Location | 11q13.3 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | RT-PCR |
| Disease | MS |
| Disease subtype | RRMSã€SPMSã€PPMS |
| Population | N/A |
| Sample Size | 23 relapsing remitting (RR), 19 secondary progressive (SP) and 12 primary progressive (PP) MS patients, as well as of 29 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 24603611 |
| Year | 2014 |
| Title | FADD is upregulated in relapsing remitting multiple sclerosis |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | FADD expression was significantly elevated in RR MS patients compared to the other disease courses |
| Mechanism/Pathway | an elevated general inflammatory activity |
