Basic information of GAS5 :
| Official Symbol of Gene | GAS5 |
| Species | Homo sapiens |
| Entrez Gene ID | 16355 |
| Official Full Name | growth arrest specific 5 |
| Also known as | SNHG2; NCRNA00030 |
| Gene Type | ncRNA |
| dbXrefs | Ensembl:ENSG00000234741 MIM:608280; AllianceGenome:HGNC:16355 |
| Map Location | 1q25.1 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | RT-qPCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | n = 108 (case group)/n = 104 (control group) |
Literature information of multiple sclerosis :
| Pubmed ID | 32348112 |
| Year | 2020 |
| Title | LncRNA GAS5 and miR-137 Polymorphisms and Expression are Associated with Multiple Sclerosis Risk: Mechanistic Insights and Potential Clinical Impact |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | Serum GAS5 was upregulated, while serum miR-137 was downregulated in MS compared with the controls. |
| Mechanism/Pathway | The long noncoding RNA GAS5 acts as a competing endogenous RNA for microRNA-137 and is involved in demyelination |
