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Basic information of MIR146A :

Official Symbol of Gene MIR146A
Species Homo sapiens
Entrez Gene ID 31533
Official Full Name microRNA 146a
Also known as MIRN146; MIRN146A; miR-146a; miRNA146A
Gene Type ncRNA
dbXrefs Ensembl:ENSG00000283733 MIM:610566; miRBase:MI0000477; AllianceGenome:HGNC:31533
Map Location 5q33.3

Sample information of multiple sclerosis:

Detected Sample peripheral blood
Sample Detail N/A
Detected Method qPCR
Disease MS
Disease subtype CIS、RRMS
Population N/A
Sample Size 15 CIS patients and 61 RRMS and 32 controls

Literature information of multiple sclerosis :

Pubmed ID 34503396
Year 2022
Title The expression and prognostic value of miR-146a and miR-155 in Turkish patients with multiple sclerosis

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result However, significant dysregulations were identified in miRNA expression in the vitamin D level, EDSS values, and the number of attacks
Mechanism/Pathway It is possible that miR-146a may be associated with vitamin D deficiency and disease disability