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Basic information of VIPR1 :

Official Symbol of Gene VIPR1
Species Homo sapiens
Entrez Gene ID 7433
Official Full Name vasoactive intestinal peptide receptor
Also known as II; HVR1; RDC1; V1RG; VIPR; VIRG; VAPC1; VPAC1; VPAC1R; VIP-R-1; VPCAP1R; PACAP-R2; PACAP-R-2
Gene Type protein coding
dbXrefs Ensembl:ENSG00000114812 MIM:192321; AllianceGenome:HGNC:12694
Map Location 3p22.1

Sample information of multiple sclerosis:

Detected Sample blood
Sample Detail N/A
Detected Method Real Time-PCR
Disease MS
Disease subtype N/A
Population N/A
Sample Size MS patients (n = 20) and healthy controls (n = 20)

Literature information of multiple sclerosis :

Pubmed ID 17077178
Year 2006
Title Altered expression of vasoactive intestinal peptide receptors in T lymphocytes and aberrant Th1 immunity in multiple sclerosis

Results of multiple sclerosis :

Expression down-regulated
Risk type Disease risk
Result Differential expression of VPAC1 and VPAC2 genes in unstimulated and activated CD4+ T cells derived from MS patients and healthy controls.
Mechanism/Pathway Both VPAC1 and VPAC2 are membrane proteins of 457 and 438 amino acids in length, respectively.