Basic information of NUPR1 :
| Official Symbol of Gene | NUPR1 |
| Species | Homo sapiens |
| Entrez Gene ID | 29990 |
| Official Full Name | nuclear protein 1, transcriptional regulator |
| Also known as | P8; COM1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000176046 MIM:614812; AllianceGenome:HGNC:29990 |
| Map Location | 16p11.2 |
Sample information of multiple sclerosis:
| Detected Sample | brain |
| Sample Detail | N/A |
| Detected Method | RT-qPCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | n = 3 |
Literature information of multiple sclerosis :
| Pubmed ID | 16374777 |
| Year | 2006 |
| Title | Upregulation of the Stress-Associated Gene p8 in Mouse Models of Demyelination and in Multiple Sclerosis Tissues |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | Real-time PCR analysis revealed a dramatic upregulation of p8 in all plaque tissues tested compared with NAWM and NAGM |
| Mechanism/Pathway | p8 is found upregulated (8×) in post-mortem tissue from MS patients and is higher in the plaque tissue compared with adjacent normal-appearing white and gray matter. |
