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Basic information of VIPR2 :

Official Symbol of Gene VIPR2
Species Homo sapiens
Entrez Gene ID 7434
Official Full Name vasoactive intestinal peptide receptor 2
Also known as VPAC2; VPAC2R; VIP-R-2; VPCAP2R; PACAP-R3; DUP7q36.3; PACAP-R-3; C16DUPq36.3
Gene Type protein coding
dbXrefs Ensembl:ENSG00000106018 MIM:601970; AllianceGenome:HGNC:12695
Map Location 7q36.3

Sample information of multiple sclerosis:

Detected Sample blood
Sample Detail N/A
Detected Method Real Time-PCR
Disease MS
Disease subtype N/A
Population N/A
Sample Size MS patients (n = 20) and healthy controls (n = 20)

Literature information of multiple sclerosis :

Pubmed ID 17077178
Year 2006
Title Altered expression of vasoactive intestinal peptide receptors in T lymphocytes and aberrant Th1 immunity in multiple sclerosis

Results of multiple sclerosis :

Expression up-regulated
Risk type Disease risk
Result Differential expression of VPAC1 and VPAC2 genes in unstimulated and activated CD4+ T cells derived from MS patients and healthy controls.
Mechanism/Pathway Both VPAC1 and VPAC2 are membrane proteins of 457 and 438 amino acids in length, respectively.