Basic information of IL17A :
| Official Symbol of Gene | IL17A |
| Species | Homo sapiens |
| Entrez Gene ID | 3605 |
| Official Full Name | interleukin 17A |
| Also known as | IL17; CTLA8; IL-17; ILA17; CTLA-8; IL-17A |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000112115 MIM:603149; AllianceGenome:HGNC:5981 |
| Map Location | 6p12.2 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS/PPMS/SPMS |
| Population | NA |
| Sample Size | 135MS/135Control |
Literature information of multiple sclerosis :
| Pubmed ID | 28717429 |
| Year | 2017 |
| Title | Circulating concentrations of interleukin (IL)-17 in patients with multiple sclerosis: Evaluation of the effects of gender, treatment, disease patterns and IL-23 receptor gene polymorphisms |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | These results indicated higher levels of IL-17 in MS patients that may be influenced by disease patterns, medication and gender. No association was observed between investigated SNPs and MS. |
| Mechanism/Pathway | Interleukin (IL)-17/IL-23 axis performs a prominent role in the pathogenesis of several autoimmune disorders. |
