Basic information of MIR18A :
| Official Symbol of Gene | MIR18A |
| Species | Homo sapiens |
| Entrez Gene ID | 406953 |
| Official Full Name | microRNA 18a |
| Also known as | MIR18; MIRH1; MIRHG1; MIRN18; miR-18; MIR17HG; MIRN18A; mir-18a; C13orf25; miRNA18A; hsa-mir-18; hsa-mir-18a |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000283815 MIM:609417; miRBase:MI0000072; AllianceGenome:HGNC:31548 |
| Map Location | 13q31.3 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | real-time PCR. |
| Disease | MS |
| Disease subtype | MS |
| Population | NA |
| Sample Size | 32MS/32Control |
Literature information of multiple sclerosis :
| Pubmed ID | 32582802 |
| Year | 2020 |
| Title | Analysis of MicroRNA-18a Expression in Multiple Sclerosis Patients |
Results of multiple sclerosis :
| Expression | down-regulation |
| Risk type | Disease risk |
| Result | miR-18a-5p expression was significantly less in MS patients than in healthy subjects. |
| Mechanism/Pathway | In multiple sclerosis (MS), the immune system acts against myelin lesions of the central nervous system, destroying neuronal fibers resulting in signal transmission disturbances in the nervous system. |
