Basic information of HTN1 :
| Official Symbol of Gene | HTN1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3346 |
| Official Full Name | histatin 1 |
| Also known as | HIS1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000126550 MIM:142701; AllianceGenome:HGNC:5283 |
| Map Location | 4q13.3 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | MS |
| Population | NA |
| Sample Size | elevated (n = 19) or normal (n = 18) |
Literature information of multiple sclerosis :
| Pubmed ID | 32440368 |
| Year | 2019 |
| Title | Serum Histidine is Lower in Fatigued Women with Multiple Sclerosis |
Results of multiple sclerosis :
| Expression | down-regulation |
| Risk type | Disease risk |
| Result | These results provide evidence that serum histidine is lower in fatigued women with MS, but the study did not find a relationship between histidine and TNF, IFN-y, or leptin gene expression. |
| Mechanism/Pathway | Disabling persistent perceived fatigue occurs in 50% of people with multiple sclerosis (MS), but mechanisms are poorly understood. |
