Basic information of IL2 :
| Official Symbol of Gene | IL2 |
| Species | Homo sapiens |
| Entrez Gene ID | 3558 |
| Official Full Name | interleukin 2 |
| Also known as | IL-2; TCGF; lymphokine |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000109471 MIM:147680; AllianceGenome:HGNC:6001 |
| Map Location | 4q27 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | MS |
| Population | Iranian population |
| Sample Size | 100MS/100Control |
Literature information of multiple sclerosis :
| Pubmed ID | 24959373 |
| Year | 2014 |
| Title | The association of -330 interleukin-2 gene polymorphism with its plasma concentration in Iranian multiple sclerosis patients |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | Accordingly, the plasma levels of IL2 were significantly higher (P < 0.0001) in patients when compared to the control group. In conclusion, in case of MS patients the -330 T/T IL2 genotype is associated with higher plasma levels of IL2. |
| Mechanism/Pathway | Multiple sclerosis (MS) is a chronic neuroinflammatory demyelinating disease of the central nervous system. The cytokine genes are involved in autoimmune diseases such as MS. |
