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Basic information of MYT1 :

Official Symbol of Gene MYT1
Species Homo sapiens
Entrez Gene ID 4661
Official Full Name myelin transcription factor 1
Also known as MTF1; MYTI; NZF2; PLPB1; ZC2H2C1; ZC2HC4A; C20orf36
Gene Type protein coding
dbXrefs Ensembl:ENSG00000196132 MIM:600379; AllianceGenome:HGNC:7622
Map Location 20q13.33

Sample information of multiple sclerosis:

Detected Sample brain
Sample Detail N/A
Detected Method N/A
Disease MS
Disease subtype N/A
Population N/A
Sample Size 8 MS patients and 2 controls

Literature information of multiple sclerosis :

Pubmed ID 17330875
Year 2007
Title Myelin transcription factor 1 (Myt1) expression in demyelinated lesions of rodent and human CNS

Results of multiple sclerosis :

Expression up-regulated
Risk type Disease risk
Result MS lesions demonstrated increased Myt1 expression in both the periplaque white matter adjacent to lesions and within early remyelinating lesions.
Mechanism/Pathway Myelin transcription factor 1 (Myt1) is a zinc-finger DNA binding protein