Basic information of PINK1-AS :
| Official Symbol of Gene | PINK1-AS |
| Species | Homo sapiens |
| Entrez Gene ID | 100861548 |
| Official Full Name | PINK1 antisense RNA |
| Also known as | NAPINK1; PINK1AS; PINK1-AS1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000117242 AllianceGenome:HGNC:38872 |
| Map Location | 1p36.12 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | NA |
| Sample Size | 50MS/50Health |
Literature information of multiple sclerosis :
| Pubmed ID | 33161812 |
| Year | 2019 |
| Title | Expression analysis of PINK1 and PINK1-AS in multiple sclerosis patients versus healthy subjects |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | Based on the altered expression of PINK1-AS in the peripheral blood of MS patients, PINK1-AS might be a putative culpript in the pathogenesis of MS. We recommend conduction of additional studies to unravel the mechanism of PINK1-AS partake in the MS |
| Mechanism/Pathway | Recent investigations which have aimed at unrav-eling the etiology of multiple sclerosis (MS), have underscored the role of mitochondria in this disorder. PINK1 gene codes a serine/threonine kinase that protects mitochondria and main-tains its normal function. |
