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Basic information of LILRA3 :

Official Symbol of Gene LILRA3
Species Homo sapiens
Entrez Gene ID 11026
Official Full Name leukocyte immunoglobulin like receptor A3
Also known as HM31; HM43; ILT6; LIR4; CD85E; ILT-6; LIR-4
Gene Type protein coding
dbXrefs MIM:604818
Map Location 19q13.4

Sample information of multiple sclerosis:

Detected Sample peripheral blood
Sample Detail NA
Detected Method PCR
Disease MS
Disease subtype RRMS/PPMS/SPMS
Population Caucasian German and French MS patients
Sample Size 723 cases and 751 controls

Literature information of multiple sclerosis :

Pubmed ID 15815690
Year 2005
Title Association of multiple sclerosis with ILT6 deficiency

Results of multiple sclerosis :

Expression down-regulation
Risk type Disease risk
Result ILT6 deficiency is associated with MS in the German population and hence a likely risk factor for autoimmune disorders
Mechanism/Pathway Family studies have shown strong genetic contributions. Linkage analyses have revealed several regions harboring risk genes including chromosome region 19q13.