Basic information of DDX5 :
| Official Symbol of Gene | DDX5 |
| Species | Homo sapiens |
| Entrez Gene ID | 1655 |
| Official Full Name | DEAD-box helicase 5 |
| Also known as | p68; HLR1; G17P1; HUMP68 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000108654 MIM:180630; AllianceGenome:HGNC:2746 |
| Map Location | 17q23.3 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | RT-PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | NA |
| Sample Size | 83MS/44Control |
Literature information of multiple sclerosis :
| Pubmed ID | 33068674 |
| Year | 2020 |
| Title |
The expression analyses of RMRP, DDX5, and RORC in RRMS patients treated with different drugs versus na |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Treatment risk |
| Result | Further-more, RMRP has demonstrated moderate positive correlations with the expression of DDX5 and RORC in treated RRMS patients. |
| Mechanism/Pathway | Although T helper 17 (Th17) lymphocytes protect mucosal barriers against infections, they have been implicated in the development of multiple sclerosis (MS). |
