Basic information of RMRP :

Official Symbol of Gene	RMRP
Species	Homo sapiens
Entrez Gene ID	6023
Official Full Name	RNA component of mitochondrial RNA processing endoribonuclease
Also known as	CHH; NME1; RRP2; RMRPR
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000277027 MIM:157660; AllianceGenome:HGNC:10031
Map Location	9p13.3

Sample information of multiple sclerosis:

Detected Sample	peripheral blood
Sample Detail	NA
Detected Method	RT-PCR
Disease	MS
Disease subtype	RRMS
Population	NA
Sample Size	83MS/44Control

Literature information of multiple sclerosis :

Pubmed ID	33068674
Year	2020
Title	The expression analyses of RMRP, DDX5, and RORC in RRMS patients treated with different drugs versus nave patients and healthy controls

Results of multiple sclerosis :

Expression	up-regulation
Risk type	Treatment risk
Result	Among the comparisons of their expressions in the different groups of treated patients with treatment-nave patients, only the down-regulation of the RMRP expression level was significant in IFNβ-1α-treated patients
Mechanism/Pathway	Although T helper 17 (Th17) lymphocytes protect mucosal barriers against infections, they have been implicated in the development of multiple sclerosis (MS).